In this passage, Paul is exposing a hearsay that was a form of Gnosticism -- that the value was in the accumulation of knowledge. Paul disproves this, saying that knowledge alone is empty -- it is the changed life and closer relationship with God that is worth anything. It is important to have knowledge, but it is only the way we use that knowledge that matters.
Knowing God is not a secret knowledge for a select few, instead, it is open to anyone who will ask God for spiritual wisdom and understanding. We learn more about God and from God to put into practice to help others and live a changed life.
Dear Lord,I pray for complete knowledge of our will and to give me spiritual wisdom and understanding. Help me to apply this to my life and help others.